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(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate

cyclophosphamide

CAS: 50-18-0

Molecular Formula: C7H15Cl2N2O2P

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(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Names and Identifiers

Name cyclophosphamide
Synonyms cyclophosphamide
Cyclophosphamide
Cyclophosphamide Sterile
2-H-1,3,2-Oxazaphosphorinane
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-(Bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphorinane 2-oxide
2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide
2-(Di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane 2-oxide
2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphosphorin-2-amine, N,N-bis(2-chloroethyl) tetrahydro-, 2-oxide
(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate
CAS 50-18-0
EINECS 200-015-4
InChI InChI=1/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Physico-chemical Properties

Molecular FormulaC7H15Cl2N2O2P
Molar Mass261.09
Density1.33±0.1 g/cm3(Predicted)
Melting Point41-45°C
Boling Point336.1±52.0 °C(Predicted)
Flash Point157.1°C
Water SolubilitySoluble. 1-5 g/100 mL at 23 ºC
Solubility Soluble in water, slightly soluble in ethanol, benzene, ethylene glycol, carbon tetrachloride, diane, almost insoluble in ether and acetone
Vapor Presure0.000115mmHg at 25°C
AppearanceWhite or white-like crystals or crystalline powders
pKa2.84±0.20(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Store in freezer, under -20°C
StabilityStable, but light sensitive. Incompatible with oxidizing agents.
Sensitive`sensitive` to heat, light and air
MDLMFCD00149395
Physical and Chemical PropertiesMelting point 41-45°C
water-Soluble solubles. 1-5g/100 mL at 23°C
UseBroad-spectrum antineoplastic agents for the treatment of leukemia and other tumors

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Risk and Safety

Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
UN IDsUN 1851
Hazard Class6.1(b)
Packing GroupIII
ToxicityLD50 oral in rat: 100mg/kg

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Reference

Reference
Show more
1. Nieluxia, Liao shuiheng, Yuan shuogang, Ma Shaodan. Study on liver and kidney toxicity of Zhangzhi Shengbai decoction based on low immunity model mice [J]. Clinical research of Traditional Chinese Medicine, 2016,8(23):8-11.
2. Zhou Xiaolu, Chen Chongjun, ran Lisha, etc. Formulation optimization and safety evaluation of compound brick tea bag [J]. Modern food science and technology, 2020, v.36;No.248(04):216-225.
3. Li Shuyan, Wang Yuhua, Wu Dongxing, etc. Establishment and discussion of a method for establishing rat model of acute enteritis [J]. Chinese traditional medicines, 2018, 40(002):444-446.
4. Cao Luoyun, Li Tianjiao, Meng Xiansheng, etc. Effects and mechanisms of Sophora tonkinensis alkaloids on DEN-induced hepatocarcinoma in rats [J]. China Modern Applied Pharmacy, 2018, 035(003):370-374.
5. Liu Hanbin, 2], Peng Jiaojiao, etc. Effects of qiangji powder on the expression of spleen transcription factors GATA-3 and T-bet in immunosuppressed mice [J]. Guangdong Agricultural Sciences, 2014(19).
6. Zhang Weibin, fan dance, Zhang Min, et al. Effect of water extract of Platycodon grandiflorum and its main component platycodin D on pharmacokinetics of cyclophosphamide [J]. Chinese herbal medicines, 2016, 39(011):2633-2635.
7. Chen Longyun, Zhou Yanyan, Anli Xu, wait. Immunoregulatory effects of quercitrin on immunosuppressed mice [J]. Chinese Journal of Immunology, 2019(19).
8. Chen Xuejuan, Jiang Yi, Li Min, Li Peining, Sun Xia, Chen Ziling, Qiu Zhifeng, Huang Yufeng. Micronucleus rate of bone marrow cells induced by M-Phenylenediamine and p-phenylenediamine in mice was detected by acridine orange-flow cytometry [J]. Laboratory animal and comparative medicine, 2019,39(03):231-235.
9. Li Peining, Jiang Yi, Chen Xiujuan, Liu Xiangmei, Peng zengxiong, Huang Yufeng. Comparison of the effects of three common positive controls in teratogenic test [J]. Canceration · aberration · mutation, 2017,29(03):235-240.
10. Wang Jianyan, Jia Mengran, Hu Yanjun, etc. Protective effect of Qishen oral liquid on immunocompromised mice [J]. Chinese agricultural bulletin, 2013, 26 (11):24-28.
11. Hu Jiayu, Chang ruoku, Liu Baijun, etc. Toxicity of Staphylococcus S-35 in mice [J]. Pesticides, 2020, v.59(05):38-42.
12. Chen Lie, Sun Sheng, Yu Changxia, etc. Isolation of lactic acid bacteria from traditional foods in northwest China and screening of immune enhancing strains [J]. China Dairy Industry, 2019(10).
13. Shi Qiang, Zheng Yongbin, Yu Fengying, etc. Effects of nicotine on micronucleus of bone marrow cells in mice [J]. Chinese Journal of Aesthetic Medicine, 2011, 20(0 z6):118,120.
14. Li Xiao, Gao Huiyan, Zhu Tonglin, et al. Immunoprotective effect of donkey-hide gelatin on cyclophosphamide-induced immunosuppression in mice [J]. Journal of Jining Medical University, 2019, 42(6):385-389.
15. Lu Yan, Li Yafei, Xiao Qianwen, et al. Pharmacokinetics of marbofloxacin in mice infected with Pasteurella multocida [J]. Chinese veterinary science, 2016, 3 (9):1183-1188.
16. Hao Lijuan, Li Ruijuan, Xi Nan, etc. Effect of Astragalus polysaccharide on peripheral blood of blood deficiency model chicken [J]. Chinese Journal of Animal Science and Veterinary Medicine, 2014, 41(4):255-257.
17. Wu Yu, Rui bin, Ye Feng, et al. Effect of propofol down-regulating miR-93-5p expression on proliferation and invasion of breast cancer MDA-MB-231 cells [J]. Chinese pharmacist 2020 v.23(06):48-53.
18. Ma Xiaoping, Yang Qiuxia, Yu cast, etc. Comparison of some biological characteristics and drug sensitivity test between wild strain (Z20) and mutant strain (Zt) of Cladosporium from giant panda [J]. Journal of Agricultural Sciences of Zhejiang, 2018(8):1328-1335.
19. He Qiaomei, Yu Fangfang, Sun Xi, Ding Xiaodan, Yuan Xiaojie, Zhang Yan, Song Xianmin. Construction of mixed chimerism mouse model of allogeneic bone marrow transplantation and analysis of influencing factors [J]. Chinese Journal of Experimental Hematology, 2021,29(02):603-609.
20. Li Yingxue, Wang Ruiyin, Bao Yongming. Synergistic Anti-tumor effect and mechanism of apigenin and Tanshinone Ⅱ_a [J]. Chinese herbal medicine, 2020,51(22):5788-5797.
21. Li Li, Liu Xiaoyi, Su Liu Yan, Jiang Xin, Zhang Yi, Wang Rui Rui. Study on the effect and mechanism of the extract of Panax notoginseng and Fluconazole against drug resistant Candida albicans [J]. Chinese Journal of Traditional Chinese Medicine, 2021,39(01):51-57 269-273.
22. Luo Liang, Li Xinman, Ma Jingyi, Lin Ju pure, Fu Hualin, Gu Jian, He Li, Yuan Zhixiang. Study on immune activity of different polar parts of white asparagus juice and residue alcohol extract [J]. Central South pharmacy, 2021,19(03):397-401.
23. Wang Danyang, Zhu Xiaoqing, Gu Xinli, Wang Mengmeng, Sun guokei, Wu Mengli, Wang Hong, Ding Yan, Luo Yan, Lian kesun. Study on the antibacterial effect in vitro and immune regulation in vivo of selenium Glycyrrhiza polysaccharide combined with antibiotics [J]. Chinese veterinary science, 2021,51(01):126-134.
24. Aidan, Chang ruokui, Zhang Bin, Yu Weiwei, Wang Yuanhong. The toxic effect of megmice yeast T-2 on mice by Intragastric Administration [J]. Food Research and Development, 2020,41(22):1-6.
25. Zhang Lin, Zhang Liang, Xiao Shengxiong, Yao Feihong, Zhang Hui. Experimental study on micronucleus of mouse LD_(50) and bone marrow cells by neodymium salicylate thioproline complex [J]. Guangdong chemical industry, 2020,47(16):63-64.
26. Niujiayou, Yuan Jing, Wei Ran, Zhang Xiaofu, Zhang Huafang, Jia Jinyu, Zhao Wen. Protective effect and mechanism of jujube polysaccharide on intestinal immune barrier in mice [J]. Science and Technology of food industry, 2021,42(04):295-300 306.
27. [IF = 5.79] Yu Yang et al."Novel partners with colistin to increase its in vivo therapeutic effectiveness and prevent the occurrence of colistin resistance in NDM- and MCR-co-producing Escherichia coli in a murine infection model."J Antimicrob Chemoth. 2019 Jan;74(1)
28. [IF=4.759] Li Zhou et al."Independent or integrative processing approach of metabolite datasets from different biospecimens potentially affects metabolic pathway recognition in metabolomics."J Chromatogr A. 2019 Feb;1587:146
29. [IF=9.229] Sheng Xu et al."Fabrication of a Silk Sericin Hydrogel System Delivering Human Lactoferrin Using Genetically Engineered Silk with Improved Bioavailability to Alleviate Chemotherapy-Induced Immunosuppression."Acs Appl Mater Inter. 2021;13(38):45175-45190
30. [IF=7.514] Tingting Ma et al."Effects of co-fermented collagen peptide-jackfruit juice on the immune response and gut microbiota in immunosuppressed mice."Food Chem. 2021 Dec;365:130487
31. [IF=5.64] Yan Yong et al."Exogenous Citrulline and Glutamine Contribute to Reverse the Resistance of Salmonella to Apramycin."Front Microbiol. 2021; 12: 759170
32. [IF=4.411] Feng Liu et al."Immunomodulatory Activity of Carboxymethyl Pachymaran on Immunosuppressed Mice Induced by Cyclophosphamide."Molecules. 2021 Jan;26(19):5733
33. [IF=2.863] Jian Zhang et al."Immunomodulatory effects of selenium-enriched peptides from soybean in cyclophosphamide-induced immunosuppressed mice."Food Sci Nutr. 2021 Nov;9(11):6322-6334
34. [IF=4.219] Yiqun Li et al."Emodin-8-O-β-D-glucopyranoside, a natural hydroxyanthraquinone glycoside from plant, suppresses cancer cell proliferation via p21-CDKs-Rb axis."Toxicol Appl Pharm. 2022 Mar;438:115909

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Standard

Authoritative Data Verified Data

This product is P-[N ,N-bis (B-chloroethyl)] -l-oxo-3-nitro-2-phospho-cyclohexane-oxide monohydrate. The content of C7H15Cl22N2O2P was 98.0% to 102.0% based on the water-free content.

Last Update：2024-01-02 23:10:35

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Trait

Authoritative Data Verified Data
  • This product is white crystal or crystalline powder; Loss of crystal water is liquefaction.
  • This product is soluble in ethanol, soluble in water or acetone.

melting point

take this product, without drying, according to the determination (General 0612), melting point of 48.5~52°C.

Last Update：2022-01-01 13:32:32

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Introduction

Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent that connects alkyl to the guanine base of DNA. Cross-linking with DNA, causing DNA strand breaks and causing mutations. Has a cytotoxic effect.
Last Update：2022-10-16 17:25:31

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Differential diagnosis

Authoritative Data Verified Data
  1. take this product about O.lg and anhydrous sodium carbonate lg, mix in the crucible, heat and melt, cool, add water 20ml to dissolve, filter; After the filtrate is made acidic by adding nitric acid, the chloride is identified (1) reaction with phosphate identification reaction (General 0301).
  2. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.
  3. The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 218).
Last Update：2022-01-01 13:32:32

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Exam

Authoritative Data Verified Data

acidity

take 0.20g of this product, Add 10ml of water to dissolve it, and immediately measure it according to law (General rule 0631). The pH value should be 4.5~6.5.

clarity and color of solution

take 0.20g of this product and add 0902 of water to dissolve the solution. The solution should be clear and colorless. If it is turbid, it should not be more concentrated compared with No. 1 turbidity standard solution (General rule first method), it shall not be deeper in comparison with the yellow No. 1 Standard Colorimetric solution (General rule 0901 first method). (For injection)

chloride

take 0.40g of this product, check according to law (General rule 0801), immediately observe, compared with the control solution made of standard sodium chloride solution 7.2ml, not more concentrated (0.018%).

phosphate

take 0.10g of this product, add 100ml of water to dissolve, add ammonium molybdate solution (take 2.5g of ammonium molybdate, add water 20tnl, heat to dissolve; Take another 50ml of water, add 28ml of sulfuric acid, shake, cool, mix the above two solutions, shake well, dilute 100ml with water) 4ml, add acid stannous chloride solution (1ml acid stannous chloride solution before use, add 2mol/L hydrochloric acid solution 10ml, shake well) 0.1 mL, shake well, place for 10 minutes, if color, and take standard phosphate solution (take appropriate amount of potassium dihydrogen phosphate, add water to dissolve and dilute the solution containing 5ug of phosphoric acid in 1ml) 2ml, add water 98ml, compared with the control solution prepared by the same method, not deeper (0.01%).

Related substances

take this product, add ethanol to dissolve and dilute to make a solution containing about 20mg per lml, as a test solution; Take an appropriate amount of precision, A solution containing 0.2mg per 1 ml was prepared as a control solution by quantitative dilution with ethanol. According to the thin layer chromatography (General 0502) test, absorb 10 u1 of each of the above two solutions and put them on the same GUI G thin layer plate, the mixture was developed using copper-butadiene-water-copper-propylene-anhydrous formic acid (80:12:4:2) as a developing solvent, dried under heating flow, and then heated at 110 ° C. For 10 minutes. Take another open cylinder, put a small beaker at the bottom, add equal volume of 5% potassium permanganate solution and hydrochloric acid, put the heated thin layer plate into the open cylinder while hot, cover the lid, the solution was placed in chlorine gas for 2 minutes and removed. Put the thin layer plate under the cold gas flow, remove the excess chlorine, until the bottom of the spot, drop potassium iodide starch solution (take potassium iodide 0. 75g, add 100ml of water to dissolve, heat to boiling, add 35ml of water that has added 0.5g of soluble starch while stirring, boil for 2 minutes) after 1 drop, the thin-layer plate shows only a very shallow blue color (avoid placing the thin-layer plate under a cold gas flow for a long time). Spray with potassium iodide starch solution, after 5 minutes, immediately review. If the test solution shows impurity spots (except the origin), its color should not be deeper than that of the main spot of the control solution.

moisture

take this product, according to the moisture determination method (General 0832 first method 1), the moisture content should be 6.0% ~ 7.0%.

Heavy metals

This product l.Og, inspection according to law (General Principles 0821 The first law), containing heavy metals shall not exceed 20 parts per million.

sterile

take this product, dissolve it with appropriate solvent, and treat it by membrane filtration method. Check it according to law (General rule 1101). (For aseptic dispensing)

Last Update：2022-01-01 13:32:33

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Content determination

Authoritative Data Verified Data

measured by high performance liquid chromatography (General 0512).

chromatographic conditions and system suitability test

silica gel bonded with eighteen alkyl silane was used as the filler; Acetonitrile-water (36:65) was used as the mobile phase; The detection wavelength was 195nm. The number of theoretical plates is not less than 2000 based on the cyclophosphamide peak.

assay

take about 25mg of this product, precision weighing, put it in 50ml measuring flask, add mobile phase to dissolve and dilute to the scale, shake, as a test solution, accurate measurement of 20u1 injection of human liquid chromatography, record chromatogram; Another cyclophosphamide reference substance, the same method for determination. According to the external standard method to calculate the peak area, that is.

Last Update：2022-01-01 13:32:34

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Category

Authoritative Data Verified Data

antineoplastic agents.

Last Update：2022-01-01 13:32:34

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Storage

Authoritative Data Verified Data

sealed (for oral use) or sealed (for injection), and stored at 30°C or lower.

Last Update：2022-01-01 13:32:34

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Cyclophosphamide tablets

Authoritative Data Verified Data

This product contains cyclophosphamide (C7H15Cl22N2O2P) should be labeled amount of 90.0% ~ 110.0%.

trait

This product is sugar-coated tablets, White after removing the coating.

identification

  1. take this product, remove the coating, grind, take an appropriate amount of fine powder (about 0.2g equivalent to cyclophosphamide), extract with ether, filter; After removing ether from the filtrate, the same results were obtained according to the tests (1) and (3) for the identification of the residue under the cyclophosphamide protocol.
  2. in the chromatogram recorded under the content determination item, the retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.

examination

  • acidity: take an appropriate amount of fine powder of this product (about 0.25g of cyclophosphamide), add water (20ml), shake to dissolve cyclophosphamide, filter, add several drops of phenolphthalein indicator solution to the filtrate, and use sodium hydroxide titration solution (0.lmol/ L) titration, not over 0.25.
  • relevant substances: take an appropriate amount of fine powder of this product (about 0.2g of cyclophosphamide), add 50ml of chloroform, shake for 15 minutes to dissolve cyclophosphamide, filter, evaporate the filtrate, and add 10ml of ethanol to dissolve the residue, as a test solution; The precision is suitable for
    • A solution containing 0.2mg of cyclophosphamide per 1 ml was prepared by quantitative dilution with ethanol as a control solution. Determination was performed according to the method for cyclophosphamide related substances. If the test solution shows impurity spots (except the origin), its color should not be deeper than that of the main spot of the control solution.
  • others shall be in accordance with the relevant provisions under the item of tablets (General rule 0101).

Content determination

Take 20 tablets of this product, remove the coating, precision weighing, fine grinding, precision weighing an appropriate amount (about 0.lg equivalent to cyclophosphamide), put it in a 100ml measuring flask, add 50ml of water, ultrasound for 10 minutes, cool, dilute to scale with water, shake well, filter, take 25ml of filtrate accurately, put it in a 50ml measuring flask, dilute to scale with mobile phase, shake well, as a test solution, according to the method under the item of cyclophosphamide content determination, it is obtained.

category

Same as cyclophosphamide.

specification

50mg

storage

light shielding, sealing, and storage at 30°C or lower.

Last Update：2022-01-01 13:32:35

(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate - Cyclophosphamide for Injection

Authoritative Data Verified Data

This product is a sterile crystal or powder of cyclophosphamide. Based on the average loading, cyclophosphamide (C7H15Cl22N2O2P) should be 95.0% ~ 105.0% of the labeled amount.

trait

This product is white crystal or crystalline powder.

identification

take this product, according to cyclophosphamide under the identification test, showed the same reaction.

examination

  • chloride take 1 bottle of this product, add water to dissolve to 10ml, quickly add dilute nitric acid 10ml and silver nitrate test solution 1ml, shake well, and check according to law (General rule 0801), immediately with standard sodium chloride solution 1.8M l(0.lg specifications) or 3.6 (0.2g specifications) made of the control solution (add water to make 10ml, plus dilute nitric acid 10ml and silver nitrate solution 1ml, shake, in the dark place for 5 minutes), no more concentrated (0.018%). The acidity and water content should be checked according to the method of cyclophosphamide, and should be in accordance with the regulations.
  • appropriate amount of contents under the item of difference in loading amount of related substances is taken, and ethanol is added to dissolve and prepare a solution containing about 20mg of cyclophosphamide per 1 ml as a test solution; Appropriate amount is taken for precision measurement, A solution containing 0.2mg per 1 ml was prepared as a control solution by quantitative dilution with ethanol. Determination was performed according to the method for cyclophosphamide related substances. If the test solution shows impurity spots (except the origin), its color should not be deeper than that of the main spot of the control solution.
  • the bacterial endotoxin of this product shall be taken and checked according to law (General rule 1143). The amount of endotoxin per 1 mg of cyclic amide shall be less than 0.17EU.
  • sterile take this product, dissolve and dilute with a suitable solvent to prepare a solution containing 20mg per lml, and treat it by membrane filtration method and check it according to law (General rule 1101).
  • others should comply with the relevant provisions under injection (General 0102).

Content determination

The content under the item of loading amount difference was taken and measured according to the method under the item of cyclophosphamide content measurement.

category

Same as cyclophosphamide.

specification

(1)0.lg (2)0.2g

storage

It was sealed and stored at 30 ° C. Or lower.

Last Update：2022-01-01 13:32:36
(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate
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Nantong Reform Petro-Chemical CO., LTD.
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Product Name: cyclophosphamide Request for quotation
CAS: 50-18-0
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Shanghai Yuanye Bio-Technology Co., Ltd.
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Product Name: Cyclophosphamide Visit Supplier Webpage Request for quotation
CAS: 50-18-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: cyclophosphamide Request for quotation
CAS: 50-18-0
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: cyclophosphamide Request for quotation
CAS: 50-18-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Cyclophosphamide Visit Supplier Webpage Request for quotation
CAS: 50-18-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
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(Bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide-2 hydrate
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